Oral Glucose-Lowering Agents vs Insulin for Gestational Diabetes: A Randomized Clinical Trial.

Importance: Metformin and glyburide monotherapy are used as alternatives to insulin in managing gestational diabetes. Whether a sequential strategy of these oral agents results in noninferior perinatal outcomes compared with insulin alone is unknown.

Objective: To test whether a treatment strategy of oral glucose-lowering agents is noninferior to insulin for prevention of large-for-gestational-age infants.

[Discontinuation of psychotropic medication: a critical review of the evidence].

Background: Pharmacotherapy is an effective treatment strategy for psychiatric disorders. Nevertheless, many patients discontinue their medication at some point. Evidence-based practices for patients, clinicians, and policymakers to discontinue psychotropic medication properly are therefore important.

The N400 effect captures nuances in implicit political preferences.

We conducted a study in San Antonio, Texas, in the weeks preceding the 2022 state Governor election to determine if implicit or explicit measures of political preference could predict voter behavior. We adapted an established event-related potential (ERP) paradigm showing political statements to participants one word at the time where the last word made the statement pro-Republican or pro-Democratic. Our sample of college students included decided and undecided voters, and was reflective of the demographic make-up of south-central Texas.

How the manner in which data is visualized affects and corrects (mis)perceptions of political polarization.

While the mechanisms underlying polarization are complex, scholars have consistently found a pervasive overestimation of perceptions of polarization to be a contributing factor. We argue that one mitigation strategy that can work at scale to address such misperceptions might be relatively straightforward: better data visualizations of cross-party attitudes on key issues. In a large-scale (N = 6603), international replication, we find that mode of presentation-or the manner in which data are visually presented-plays a significant role in moderating perceptions of polarization, even for longstanding, divisive issues for which partisans would likely hold strong prior beliefs.