In the past 20 years infections caused by Mycobacterioides abscessus have become increasingly common in patients with chronic lung conditions. The microorganisms are also resistant to a number of antibiotic classes, making treatment challenging. To begin understanding how the bacterium adapts to the lung environment, pure colonies of M.
View Article and Find Full Text PDFNon-tuberculous mycobacteria (NTM) are opportunistic pathogens ubiquitous in the environment. is a relatively new pathogen associated with underlying lung chronic pathologies, accounting for most of the pulmonary infections linked to the rapidly growing mycobacteria group. This includes chronic obstructive pulmonary disease, bronchiectasis, or cystic fibrosis.
View Article and Find Full Text PDFSci Total Environ
December 2024
The European Union, as delineated in Regulation (EU) 2020/741, sets forth minimum criteria for the reuse of wastewater. Directive 86/278/CEE sets the regulations for the reuse of sewage sludge in agriculture. This study aimed to investigate the treated water derived from a pilot plant situated in Granada, Spain, that utilizes membrane bioreactor technology to process real urban wastewater with the quality standards necessary for agricultural reuse.
View Article and Find Full Text PDFObjectives: Slow-growing nontuberculous mycobacteria (NTMs) are highly prevalent and routinely cause opportunistic intracellular infectious disease in immunocompromised hosts.
Methods: The activity of the triple combination of antibiotics, clarithromycin (CLR), rifabutin (RFB), and clofazimine (CFZ), was evaluated and compared with the activity of single antibiotics as well as with double combinations in an in vitro biofilm assay and an in vivo murine model of subsp. () lung infection.