Publications by authors named "L E Adinolfi"
Background: The severe acute respiratory syndrome Coronarovirus-2 associated still causes a significant number of deaths and hospitalizations mainly by the development of respiratory failure. We aim to validate lung ultrasound score in order to predict mortality and the severity of the clinical course related to the need of respiratory support.
Methods: In this prospective multicenter hospital-based cohort study, all adult patients with diagnosis of SARS-CoV-2 infection, performed by real-time reverse transcription polymerase chain reaction were included.
Article Synopsis
- The study examines muscle changes, specifically sarcopenia and myosteatosis, in cirrhosis patients to understand their prevalence and impact on health over a year.
- In a group of 433 patients, different combinations of these muscle changes were found, with notable increases in mortality and hospitalization rates linked to isolated myosteatosis and combined muscle changes.
- Findings indicate that both myosteatosis and sarcopenia are common in cirrhosis, leading to worse health outcomes, emphasizing the need for better prognostic evaluations in these patients.
Background & Aims: SARS-Cov-2 infection manifests as a wide spectrum of clinical presentation and even now, despite the global spread of the vaccine, contagiousness is still elevated. The aim of the study was the evaluation of the impact of liver fibrosis assessed by FIB-4 and liver impairment, assessed by cytolysis indices, on intrahospital mortality in COVID-19 subjects.
Methods: This is a retrospective observational cohort study, which involved 23 COVID Hospital Units in Campania Region, Italy.
Background And Aims: The COVID-19 pandemic, caused by the novel coronavirus SARS-CoV-2, has fundamentally reshaped the landscape of global public health, with some people suffering more adverse clinical outcomes than others. The aim of this study is to deepen our understanding of the specific impact of acute kidney injury (AKI) on the in-hospital mortality in octogenarian patients with COVID-19.
Methods: This is a prospective observational cohort study, which involved 23 COVID-19 hospital units in the Campania Region, Italy.
Coronavirus disease of 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may be complicated by life-threatening interstitial pneumonia. SARS-CoV-2 infection may also damage several tissues and/or organs beyond the lungs, including the liver. However, controversy still exists as to whether SARS-CoV-2-induced liver alterations can have an impact on the outcome of COVID-19.
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