Publications by authors named "L Dunk"

Article Synopsis
  • Scientists needed to find a better way to check HER2 levels in breast cancer patients because it helps decide the best treatment!
  • They tested a digital algorithm against regular microscope methods and found that the digital tool made it easier for different doctors to agree on their results!
  • Using the algorithm not only improved how often they agreed on the HER2 levels but also saved time when checking the samples!
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Background: The coronavirus pandemic has had a profound impact on the cervical screening programme in Wales for the eligible women, sample takers, and laboratory and colposcopy services.

Aims: To explore what changes due to the pandemic have adversely affected screening outcomes in Wales and what lessons can be learned to improve cervical screening in Wales and elsewhere.

Methods: A review of the screening performance in 2020 and the first quarter of 2021 in Wales as well as a comparison with other cervical screening programme responses to the pandemic.

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Objective: To determine the demand for colposcopy in the Cervical Screening Wales programme after the introduction of human papillomavirus (HPV) cervical screening, which coincided with the start of screening of women vaccinated against HPV types 16/18.

Design: The study used a computational model that assigns screening and screening-related colposcopy events to birth cohorts in individual calendar years.

Setting: Cervical Screening Wales.

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Unlabelled: Papillary carcinoma (PC) of the breast, which accounts for 0.5% to 1% of breast cancer, is a distinct histologic subtype that is characterized by malignant epithelial proliferation supported by fibrovascular stalks. However, the classification of PC (whether they are in situ or invasive), its behavior, and management remain a matter of debate.

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We present a rare case of renal metastasis of a recurrent pleomorphic adenoma of the parotid gland in an elderly woman. Metastasising pleomorphic adenoma shows malignant clinical behaviour, and although it appears histologically benign, there may be unknown molecular features that determine its unusual ability to spread.

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