Publications by authors named "L Duffy"
Aim: To identify the essential characteristics of therapeutic relational connection (TRC) as viewed by nurse practitioners (NPs) in the practice of their virtual visits caring for young adults living with chronic illness.
Design: This is a qualitative descriptive study of data obtained from open-ended items on an online questionnaire.
Methods: The sample was recruited through an electronic listserv sent by the National Association of Pediatric Nurse Practitioners (NAPNAP) to access a national sample.
We evaluated the use of the Product Enhanced Reverse Transcriptase (PERT) assay as a means of detecting virus in retroviral vectors products pseudotyped with Gibbon Ape Leukemia Virus (GALV) and Vesicular Stomatitis Virus G (VSVG) envelopes. PERT provides greater standardization than the S+/L- assay which has been used extensively in virus detection. A challenge is that PERT will also detect residual retroviral vectors as vector particles contain reverse transcriptase.
View Article and Find Full Text PDFIntroduction: This process evaluation was conducted in parallel to the randomised controlled feasibility trial of NIDUS-Professional, a manualised remote dementia training intervention for homecare workers (HCWs), delivered alongside an individualised intervention for clients living with dementia and their family carers (NIDUS-Family). The process evaluation reports on: (i) intervention reach, dose and fidelity; (ii) contexts influencing agency engagement and (iii) alignment of findings with theoretical assumptions about how the intervention might produce change.
Methods: We report proportions of eligible HCWs receiving any intervention (reach), number of sessions attended (dose; attending ≥4/6 main sessions was predefined as adhering), intervention fidelity and adherence of clients and carers to NIDUS-Family (attending all 6-8 planned sessions).
Article Synopsis
- Antidepressants are commonly prescribed for depression, but not all patients respond well, prompting a need to investigate which characteristics might influence treatment effectiveness.
- The PANDA trial compared the effectiveness of sertraline (an antidepressant) with a placebo in 655 primary care patients, examining 11 potential factors (like age, marital status, and family history) that could affect patients' responses to treatment.
- The study found that only a patient's family history of depression showed any potential impact on treatment response, suggesting those without such a history may benefit more, while other factors had no significant influence, indicating a need for ongoing conversations about antidepressant options for all patients.