Low-Dose Rituximab for Active Moderate to Severe Graves' Orbitopathy Resistant to Conventional Treatment.

: To report low-dose rituximab effect in Graves' orbitopathy (GO) resistant to conventional treatment. : Retrospective analysis of medical records, filled in according to the European Group on Graves' Orbitopathy (EUGOGO) standards, of patients with active moderate-to-severe GO who received low-dose rituximab after failure of conventional treatment. Efficacy was defined by a decrease of the clinical activity score of 2 points or <4/10.

Scoring system for predicting recurrences in patients with papillary thyroid microcarcinoma.

Context: Papillary thyroid microcarcinomas (PMC) defined as tumors ≤10 mm in diameter (including pT1a and pT3 according to the latest pTNM classification) have good prognosis, although recurrence is possible. Clinicians are interested in using a scoring system for predicting recurrences.

Objective: To identify the prognostic factors for recurrence in patients with PMC and to develop a scoring system based on lymph node involvement, multifocality, and sex.

Hyperglycemia after repeated periocular dexamethasone injections in patients with diabetes.

Purpose: To assess the hyperglycemic effect of 3 consecutive daily periocular steroid injections in patients with diabetes.

Design: Retrospective observational study in a national eye center.

Participants: Twenty-five hospitalized patients with type 2 diabetes who received a subconjunctival (n = 11) or a peribulbar injection (n = 14) with 4 mg dexamethasone disodium phosphate once a day for 3 consecutive days for ocular conditions.

Is the relationship between adherence behaviours and glycaemic control bi-directional at adolescence? A longitudinal cohort study.

Aim: To analyse the change in adherence to diabetes treatment and its association with metabolic control from childhood to adolescence. The Tanner pubertal staging model was selected as a marker of developmental maturity.

Methods: In a multicentre, longitudinal cohort study, 142 children with Type 1 diabetes completed a scale that assessed adherence to treatment and a test of diabetes knowledge at the beginning of the study (T0) and four years later (T4).