Publications by authors named "L Driver"

Importance: Ultrasonography-guided nerve blocks (UGNBs) have become a core component of multimodal analgesia for acute pain management in the emergency department (ED). Despite their growing use, national adoption of UGNBs has been slow due to a lack of procedural safety in the ED.

Objective: To assess the complication rates and patient pain scores of UGNBs performed in the ED.

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  • In July 2017, a black flying fox was found with neurological issues, leading to the discovery of a new hantavirus called Robina virus (ROBV) in its brain.
  • Research indicated that ROBV is closely related to Quezon virus, which was found in a different type of bat in the Philippines.
  • From March 2018 to October 2023, 495 bats were tested for ROBV, revealing a 4.2% prevalence, with increased detections in 2019-2020 suggesting a possible epidemic and demonstrating seasonal effects on virus spread.
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Ionizing radiation induces cell death in the gastrointestinal (GI) epithelium by activating p53. However, p53 also prevents animal lethality caused by radiation-induced acute GI syndrome. Through single-cell RNA-sequencing of the irradiated mouse small intestine, we find that p53 target genes are specifically enriched in regenerating epithelial cells that undergo fetal-like reversion, including revival stem cells (revSCs) that promote animal survival after severe damage of the GI tract.

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  • The Buffalo National River (BNR) in Arkansas is a significant water resource studied for its bacterial ecology, particularly in relation to nearby concentrated animal feed operations (CAFOs).
  • Water sampling revealed that bacterial counts (CFUs) were highest near the CAFO, while esterase activity was surprisingly lower at these locations, suggesting a complex interaction with organic enrichment.
  • Metagenomic analysis indicated that microbial diversity and activity were influenced by proximity to wastewater sources, and laboratory experiments confirmed that exposure to organic wastewater contaminants altered bacterial metabolism, particularly highlighting atrazine's negative impact.
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