Publications by authors named "L Driul"

Placental insufficiency often correlates with fetal growth restriction (FGR), a condition that has both short- and long-term effects on the health of the newborn. In our study, we analyzed placental tissue from infants with FGR and from infants classified as small for gestational age (SGA) or appropriate for gestational age (AGA), performing comprehensive analyses that included transcriptomics and metabolomics. By examining villus tissue biopsies and 3D trophoblast organoids, we identified significant metabolic changes in placentas associated with FGR.

View Article and Find Full Text PDF

Objective: We assessed reproductive, obstetrical, and oncological outcomes in patients who underwent fertility-sparing treatment by including studies that adhere to the FIGO 2018 staging system.

Methods: Data on recurrence, mortality, pregnancy rate, live birth rate, and preterm delivery rate were collected.

Results: In patients with stages IA1, IA2, and IB1, the recurrence rate was 4.

View Article and Find Full Text PDF
Article Synopsis
  • - This study aimed to evaluate how much pregnant women and hospital staff know about umbilical cord blood (UCB) donation and storage, revealing key insights into their views and practices.
  • - A total of 19 studies involving nearly 20,000 pregnant women and over 1,200 hospital staff showed that awareness of UCB was 61% for both groups, with 57% of pregnant women having a positive attitude toward UCB donation.
  • - The findings indicated a strong preference for public UCB banking over private options, with 51% of pregnant women favoring public storage compared to only 12% for private storage.
View Article and Find Full Text PDF

Background: Celiac disease (CD) is an inflammatory enteropathy that has been associated to obstetric and gynecological disorders. However, it is still not adequately tested by gynecologists due to the misconception that it is solely a gastrointestinal disease. This underestimation requires the development of targeted interventions.

View Article and Find Full Text PDF

Pregnancy and lactation-associated osteoporosis is a rare form of osteoporosis occurring during late pregnancy and early lactation, featuring fragility fractures, primarily involving the vertebral bodies and leading to back pain. Its management involves osteoporosis treatment, complicated by potential drug-related dangerous effects on the fetus. Nevertheless, many controversies remain regarding diagnosis, prognosis, and treatment options.

View Article and Find Full Text PDF