Publications by authors named "L Dricot"
Article Synopsis
- The study focuses on the early detection and intervention of unilateral cerebral palsy (UCP) in infants to enhance long-term motor skills through a specific therapy called HABIT-ILE.
- Conducted as a randomized clinical trial in Brussels, Belgium, infants aged 6 to 18 months were paired by age and lesion type and assigned to either a treatment group receiving intensive therapy or a control group maintaining usual activities.
- The effectiveness of the therapy was assessed through various motor function metrics, with the primary measurement being the use of the more affected hand, alongside additional evaluations like the Canadian Occupational Performance Measure and Gross Motor Function Measure scores.
Article Synopsis
- MRI segmentation algorithms allow detailed study of MTL structures, aiding in the search for preclinical Alzheimer’s disease (AD) biomarkers.
- In a study of 581 non-demented individuals, certain amygdala subnuclei were linked to tau deposits, but global brain volumes showed no significant changes.
- Specific atrophy in amygdala subnuclei may indicate early signs of tauopathy in individuals at risk for developing AD, while overall hippocampal volumes were not correlated with tau levels.*
Article Synopsis
- The study investigates how Vagus Nerve Stimulation (VNS) can help treat Drug-Resistant Epilepsy (DRE) by examining the role of thalamocortical tracts in the brain's response to the treatment.
- Using advanced MRI techniques, researchers analyzed the microstructural features of thalamocortical tracts in 18 DRE patients, identifying differences between those who responded to VNS and those who did not.
- A Support Vector Machine model showed a high classification accuracy (94.12%), indicating that certain structural brain characteristics are associated with treatment outcomes, with clinical factors not significantly enhancing the predictive ability.
Background: There is good evidence that elevated amyloid-β (Aβ) positron emission tomography (PET) signal is associated with cognitive decline in clinically normal (CN) individuals. However, it is less well established whether there is an association between the Aβ burden and decline in daily living activities in this population. Moreover, Aβ-PET Centiloids (CL) thresholds that can optimally predict functional decline have not yet been established.
View Article and Find Full Text PDFThe locus coeruleus-norepinephrine system is thought to be involved in the clinical effects of vagus nerve stimulation. This system is known to prevent seizure development and induce long-term plastic changes, particularly with the release of norepinephrine in the hippocampus. However, the requisites to become responder to the therapy and the mechanisms of action are still under investigation.
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