Publications by authors named "L Dovere"
Article Synopsis
- The study aimed to explore how sperm quality (based on WHO-2021 criteria) and paternal factors like BMI and age relate to outcomes in ICSI cycles with PGT-A, focusing on clinical and embryological results.
- Conducted at a private IVF clinic, the research included data from 3101 couples over several years, employing techniques like trophectoderm biopsies and chromosome testing to evaluate the success of fertilization and embryo development.
- Results showed that maternal age significantly affected embryo quality, while lower sperm motility and specific conditions like obstructive and non-obstructive azoospermia were linked to poorer outcomes, including live birth rates.
Purpose: To evaluate the impact of high thyroid stimulating hormone (TSH) levels on human granulosa-luteal (hGL) cells.
Methods: hGL cells were isolated from follicular aspirates derived from patients undergoing IVF treatment without any thyroid disorder (serum TSH 0.5-2 mU/L).
Research Question: The study aimed to retrospectively evaluate the impact of cryo-storage duration on clinical, obstetric and perinatal outcomes after vitrified-warmed euploid blastocyst transfer.
Design: This was an observational study including 2688 vitrified-warmed euploid single blastocyst transfers that was conducted at a private IVF centre between May 2013 and March 2020. It included a total of 1884 women (age 38 ± 3 years) undergoing at least one transfer after preimplantation genetic testing for aneuploidies.
Infertility affects 10%-15% of couples worldwide. Of all infertility cases, 20%-70% are due to male factors. In the past, men with severe male factor (SMF) were considered sterile.
View Article and Find Full Text PDFStudy Question: Is there an association between patients' reproductive history and the mean euploidy rates per biopsied blastocysts (m-ER) or the live birth rates (LBRs) per first single vitrified-warmed euploid blastocyst transfers?
Summary Answer: Patients' reproductive history (as annotated during counselling) showed no association with the m-ER, but a lower LBR was reported after euploid blastocyst transfer in women with a history of repeated implantation failure (RIF).
What Is Known Already: Several studies have investigated the association between the m-ER and (i) patients' basal characteristics, (ii) ovarian stimulation strategy and dosage, (iii) culture media and conditions, and (iv) embryo morphology and day of full blastocyst development. Conversely, the expected m-ER due to women's reproductive history (previous live births (LBs), miscarriages, failed IVF cycles and transfers, and lack of euploid blastocysts among prior cohorts of biopsied embryos) still needs investigations.