Publications by authors named "L Douglass"
Purpose: Anti-seizure medications (ASM) can lower the efficacy of hormonal birth control (BC), while estrogen-containing BC can increase ASM metabolism, altering seizure frequency. Despite these adverse interactions, many youth with epilepsy demonstrate inadequate knowledge about this topic. Thus, there is a need to develop tools that empower youth with epilepsy to make more informed contraceptive decisions.
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- Primary hyperparathyroidism (PHPT) can cause kidney stones, but doctors don't always check for it in patients with these stones.
- In a study of 2264 patients with kidney stones, 383 had high calcium levels, and only 107 had their parathyroid hormone (PTH) tested.
- Most patients tested had high PTH levels, but many didn't see a specialist, even though those referred had higher calcium and PTH levels.
Article Synopsis
- The study looked at how the use and cost of certain medications (non-IV rescue benzodiazepines) changed after new options (intranasal midazolam and diazepam) became available from 2016 to 2022.
- Out of 4,444 patients, over half switched from using rectal diazepam to the new intranasal options, and this trend increased each year.
- The study found that the costs for the last medication patients used were higher than for the first one, meaning those who switched to intranasal medications ended up paying more.
Article Synopsis
- The study aimed to analyze how often home, non-intravenous benzodiazepines (non-IV-rBZDs) are prescribed for kids experiencing febrile seizures and identify factors influencing these prescriptions.
- Using data from a significant database spanning 2006 to 2022, the research examined a sample of 82,835 children aged 6 months to 5 years who had febrile seizures.
- Results showed that only about 12% filled a prescription for non-IV-rBZD, with key factors like having complex febrile seizures or being hospitalized for seizures being strongly linked to whether a prescription was given.
Article Synopsis
- Extremely low gestational age newborns (ELGANs) are those born at 28 weeks or earlier and face high risks of preterm birth complications, including infant mortality and neurological issues.
- Despite advancements in care, the rate of preterm births is increasing, and neonatal seizures are a key indicator of potential long-term neurological disorders in these infants.
- The review highlights the need to understand the risk factors associated with neonatal seizures in ELGANs to improve prevention and treatment methods, while also pointing out the limitations of existing studies on the topic.