Publications by authors named "L Dorfer"
Article Synopsis
- Sepsis is a serious condition that poses risks to human health and has significant economic implications; recent research highlights various factors, including cellular senescence, that contribute to this issue.
- In an experimental study on male mice, sepsis was induced via cecal ligation and puncture, leading to noticeable pulmonary damage and increased markers associated with acute lung injury and cellular senescence.
- The results revealed complex changes in senescence-related pathways, suggesting that while some markers decrease, others may increase during the early stages, pointing to the need for further research on the long-term impacts of sepsis on multiple organ systems.
Article Synopsis
- The introduction highlights the importance of the operating room (OR) in hospitals for patient treatment, noting that the COVID-19 pandemic led to significant operational restrictions that could have long-term negative effects on OR performance.
- The methods involved a detailed analysis of perioperative processing times at the University Hospital Ulm, comparing data from the second quarters of 2019 to 2022, and included statistical testing to validate the findings.
- Results showed a 31% decrease in surgeries in 2020 and persistent delays in key OR processes beyond 2020, indicating lingering impacts of the pandemic on surgical efficiency, with average operation times and anaesthesia durations remaining elevated.
Background: Systemic and neuroinflammatory processes play key roles in neurodegenerative diseases such as Parkinson's disease (PD). Physical trauma which induces considerable systemic inflammatory responses, represents an evident environmental factor in aging. However, little is known about the impact of physical trauma, on the immuno-pathophysiology of PD.
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- * A short-time cardiovascular response known as the "Réflexe Auriculo Cardiaque" (RAC), described by Nogier in 1976, allows for the study of quick autonomic reactions to small stimuli without altering system characteristics.
- * The study found that fast heart rate changes are linked to vagal responses and slower pulse wave changes to sympathetic responses, enabling a quick and effective method for assessing the autonomic nervous system's functioning.
Background: Laser acupuncture, a painless technique, is a widely used alternative treatment method for childhood asthma, although its efficacy has not been proved in controlled clinical studies.
Methods: A double blind, placebo controlled, crossover study was performed to investigate the possible protective effect of a single laser acupuncture treatment on cold dry air hyperventilation induced bronchoconstriction in 44 children and adolescents of mean age 11.9 years (range 7.