Publications by authors named "L Dominguez-Soto"
Background: Actinic prurigo is an idiopathic photodermatosis, the pathophysiology of which has been hypothesized to involve subtype IV type b (Th2) hypersensitive response, whereby IL4, IL5, and IL13 are secreted and mediate the production of B cells, IgE, and IgG4.
Objectives: To examine the association of serum IgE levels and the clinical severity of injuries.
Methods: This case-control study comprised patients with a clinical and histopathological diagnosis of actinic prurigo, as well as clinically healthy subjects, from whom 3cc of peripheral blood was taken for immunoassay.
Article Synopsis
- Actinic prurigo is a skin condition mainly seen in indigenous and mestizo Latin American populations, characterized by itchy skin and mucosal lesions that worsen with sun exposure and typically begins in childhood.
- The exact cause is not well understood, but it involves an unusual immune response with high levels of certain immune cells, hinting at a hypersensitivity reaction.
- Diagnosis is based on clinical observation and specific histopathology findings, while thalidomide is currently the most effective treatment available despite potential side effects.
[Underestimation of dermatology and the efforts of dermatologists to benefit patients].
Rev Med Inst Mex Seguro Soc
August 2016
[Underestimation of dermatology based on ignorance and its impact on patient's health].
Rev Med Inst Mex Seguro Soc
December 2016
With the emergence of medical specialties in different areas of medicine, assessment of patients became narrow and specialized. There is also the perception that some specialties are more difficult than others. Dermatology has long been seen by most physicians non dermatologists as a relaxed area, without real emergencies or requirement of great intellectual effort.
View Article and Find Full Text PDFBackground: Actinic prurigo (AP) is an idiopathic photodermatosis that usually onsets during childhood and predominates in women. It is characterized by the symmetrical involvement of sun-exposed areas of the skin, lips, and conjunctiva.
Objectives: This study aimed to analyze the risk factors associated with AP using a case-control design.