Publications by authors named "L Domenici"

Article Synopsis
  • Vulvar lymphomas are rare tumors that are often overlooked, typically presenting as a mass in elderly patients.
  • There are no significant age differences between primary and secondary lymphomas, making diagnosis challenging.
  • Accurate diagnosis requires histological examination along with genetic and molecular profiling, but the prognosis for vulvar lymphoma is generally positive.
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Article Synopsis
  • Aggressive angiomyxoma (AAM) is a rare tumor found mostly in the pelvic area of young women, known for its slow growth and tendency to invade nearby tissues without a clear boundary.
  • Diagnosing AAM before surgery is challenging due to its rarity and lack of specific symptoms, making complete removal difficult during treatment.
  • Despite surgical excision being the primary approach, recurrence occurs in up to 40% of cases, sometimes many years later; this paper aims to provide updated information on diagnosis and management of AAM based on recent clinical experiences.
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Deep (aggressive) angiomyxoma of the lower genital tract is a rare malignancy affecting women of reproductive age. Being a hormone-sensitive tumor, its growth is particularly benefitted during pregnancy. Surgical excision with complete resection is indicated, even if a wait-and-see approach can be considered until delivery, to avoid destructive surgeries.

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Objective: An increasing number of robotic hysterectomies are being performed and the most common indication is fibroids. Fibroid uterus is common indication for hysterectomy for enlarged uteri. The role of robotic approach for complex pathologies as enlarged uterus is still debatable.

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Introduction: Increasing evidence demonstrates a crucial role of inflammation in inducing and promoting several cancers. Pro-inflammatory upregulation of cytokines such as IL-6 has been implicated in cervical cancer development and progression through several mechanisms, for example, by inducing platelet production, activation, and aggregation. The aim of the study was to evaluate the effective prognostic impact of inflammatory biomarkers such as platelet count, platelet to lymphocyte ratio (PLR), and IL-6 in cervical cancer patients.

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