Publications by authors named "L Djansugurova"

Article Synopsis
  • * Findings show high genetic diversity in the Kazakh Tobet, classified into seven distinct genetic clusters, indicating its complex genetics.
  • * The research suggests shared ancestry with breeds like the Central Asian Shepherd Dog and Turkish Akbash, and highlights the breed's ancient origins, providing a foundation for preservation and international recognition.
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Article Synopsis
  • Organochlorine pesticides (OCPs) differ in chemical structure and toxicity mechanisms but share common traits like persistence and bioaccumulation, contributing to health problems.
  • Despite extensive knowledge on OCP toxicity, the specific molecular mechanisms impacting mammals remain partially unknown, prompting this review to explore their modes of action.
  • The review focuses on three widely used OCPs—Dichlorodiphenyltrichloroethane, Hexachlorocyclohexane, and Chlordecone—examining their biological responses and interactions in human and animal bodies.
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Biochars (BCs) and activated carbons (ACs) are well-known carbon-rich materials that are being increasingly studied in environmental sciences for water treatment applications to remediate pollutant sequestration in soil. This study aimed to assess the impact of Sargasso BC particle size and amendment rate on the environmental availability of DDT and DDT metabolites in two distinct Kazakh soils. These two soils were collected in the vicinity of storehouse facilities in Kyzylkairat and Beskainar that store banned pesticides.

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Breast cancer is a global health problem. It is an age-dependent disease, but cases of early-onset breast cancer (eBC) are gradually increasing. There are many unresolved questions regarding eBC risk factors, mechanisms of development and screening.

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The association of genetic polymorphisms with the individual sensitivity of humans to the action of pesticide pollution is being actively studied in the world. The aim of this study was a molecular epidemiological analysis of candidate polymorphisms of genes involved in pesticide metabolism, detoxification, and antioxidant protection. Some of the selected polymorphisms also relate to susceptibility to cancer and cardiovascular, respiratory, and immune system diseases in individuals exposed to pesticides for a long time.

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