Cutaneous manifestations of disseminated cryptococcosis.

Disseminated cryptococcosis is a life-threatening infection with cutaneous dissemination in 10% to 20% of cases. We describe seven patients with disseminated cryptococcosis with variable cutaneous manifestations. AIDS was a predisposing factor in six patients.

Photodynamic therapy for the treatment of squamous cell carcinoma using benzoporphyrin derivative.

Background: Photodynamic therapy (PDT) involves laser light excitation of a tumor-localizing photosensitizer to destroy neoplasms. Benzoporphyrin derivative (BPD) is a new photosensitizer with several favorable characteristics.

Objective: Studies were designed to: 1) assess the efficacy of BPD-mediated PDT in treating in vivo squamous cell carcinomas (SCC); 2) obtain dosimetry data for BPD and laser parameters; and 3) establish clinical and histologic correlates of BPD-induced tumor regression.

Malignant clear cell hidradenoma: a case report and literature review.

Malignant clear cell hidradenoma is an uncommon variant of sweat gland tumors. Histological sections show lobulated masses and anastomising cords of cells which were polygonal to slightly fusiform in appearance. Most of the cells have bland appearing ovoid nuclei with slightly eosinophilic to clear cytoplasm.

Atypical chondroid syringoma.

In summary, chondroid syringoma is a rare sweat gland neoplasm characterized by its slow growth and unpredictable growth phase. When malignant, it has a significant potential for recurrence, metastases, and even death. Due to the rarity of this tumor, an accurate preoperative diagnosis is difficult.