Publications by authors named "L Diaconu"
Article Synopsis
- Sarcopenia and frailty are common problems in patients with advanced liver disease that can negatively affect health outcomes, making their assessment and management crucial.
- A study conducted in Romania from 2021 to 2023 analyzed 128 patients using various physical assessments to determine the prevalence of these conditions, revealing that younger patients were often affected.
- The findings showed that patients with both sarcopenia and frailty had poorer survival rates and higher complications, emphasizing the need for early intervention in this population.
Effectiveness of 8-week Treatment with Glecaprevir/Pibrentasvir in Treatment-naïve or -experienced HCV Patients: Results from an Observational Retrospective Study in Real-life Settings (ODYSSEY).
J Gastrointestin Liver Dis
December 2024
Background And Aims: Pan-genotypic ribavirin-free oral direct-acting antivirals, including the glecaprevir/pibrentasvir combination, are recommended for the treatment of most patients with chronic hepatitis C virus (HCV) infection. In Romania, the HCV-infected patient population receiving glecaprevir/pibrentasvir is not well characterized and data on treatment effectiveness is lacking. The ODYSSEY study aimed to provide insights into the characteristics and treatment outcomes of HCV-infected Romanian patients receiving 8-week therapy with glecaprevir/pibrentasvir.
View Article and Find Full Text PDF: The management of inflammatory bowel disease (IBD) includes, besides the control of symptoms, the prevention of organ damage and the improvement of the overall disability. : A single-centered, cross-sectional, non-interventional and population-based study was conducted between October 2023 and August 2024 in the Department of Internal Medicine 2 and Gastroenterology of Bucharest Emergency University Hospital to assess the disease disability and quality of life impact using IBD-disk and correlation with different parameters. : We included 112 patients; their mean age was 52.
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- The study investigates the long-term disability effects of severe COVID-19 three years after post-acute rehabilitation using the WHODAS 2.0 questionnaire.
- Out of 69 identified patients, only 27 participated, highlighting the impact of emotional distress on patient response rates; most patients were older, with comorbidities like diabetes and high blood pressure prevalent.
- Results showed a mean disability score of 35.09%, largely influenced by diabetes and central neurological deficits, suggesting a need for targeted rehabilitation and ongoing care to enhance recovery outcomes.
Assessing the Effectiveness of Rehabilitation Interventions through the World Health Organization Disability Assessment Schedule 2.0 on Disability-A Systematic Review.
J Clin Med
February 2024
(1) Background: The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a tool designed to measure disability in accordance with the International Classification of Functioning, Disability and Health.
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