Marker-based C-arm self-calibration with unknown calibration pattern.

Background: Accurate tomographic reconstructions require the knowledge of the actual acquisition geometry. Many mobile C-arm CT scanners have poorly reproducible acquisition geometries and thus need acquisition-specific calibration procedures. Most of geometric self-calibration methods based on projection data either need prior information or are limited to the estimation of a low number of geometric calibration parameters.

A tomographic reconstruction algorithm for cross-sectional imaging of IMRT beams from six projections.

. Patient-specific Quality Assurance (QA) measurements are of key importance in radiotherapy for safe and efficient treatment delivery and allow early detection of clinically relevant errors. Such QA processes remain challenging to implement for complex Intensity Modulated Radiation Therapy (IMRT) radiotherapy fields delivered using a multileaf collimator (MLC) which often feature small open segments and raise QA issues similar to those encountered in small field dosimetry.

A novel QA phantom based on scintillating fiber ribbons with implementation of 2D dose tomography for small-field radiotherapy.

Purpose: To develop a novel instrument for real-time quality assurance (QA) procedures in radiotherapy. The system implements a scintillation-based phantom and associated signal acquisition and processing modules and aims to monitor two-dimensional (2D) dose distributions of small fields.

Materials And Methods: For the proposed phantom, we have designed and realized a prototype implementing six high-resolution tissue-equivalent scintillating fiber ribbons stacked with in-plane 30° rotated orientations from each other.

Tiny changes in tomographic system matrices can cause large changes in reconstruction quality.

This paper studies the impact of tiny changes in region-of-interest (ROI) tomography system matrices on the variance of the reconstructed ROI. In small-scale and medium-scale examples, the variance in the reconstructed ROI was estimated for different system matrices. The results revealed a striking and counterintuitive phenomenon: a tiny change in the system matrix can dramatically affect the variance of the ROI estimate.

SciFi detector and associated method for real-time determination of profile and output factor for small fields in stereotactic radiotherapy.

Purpose: For determining small-field profile and output factor during stereotactic radiotherapy quality assurance (QA) procedures, we propose a novel system based on the scintillating fiber (SciFi) detector with output image acquisition and processing to allow real-time monitoring of profile and output factor.

Materials And Methods: The employed detector is a SciFi detector made of tissue-equivalent scintillating plastic fibers arranged in 6-layer fiber ribbons with a fiber pitch of 275 μm in each layer. The scintillating signal at the detector output is acquired by a sCMOS (scientific complementary metal-oxide-semiconductor) camera and represents the projected field profile along the fibers axis.