Publications by authors named "L Derex"

Article Synopsis
  • The study explored how increased oxygen extraction fraction (OEF) affects the recovery of diffusion-weighted imaging (DWI) lesions in stroke patients who underwent thrombectomy after acute ischemic events.
  • It analyzed data from the HIBISCUS-STROKE cohort, focusing on DWI and perfusion magnetic resonance imaging results to understand the relationship between OEF levels and changes in ischemic lesion volume.
  • Results showed that patients with increased OEF within their DWI lesions experienced a significant reduction in lesion volume compared to those without increased OEF, suggesting that higher OEF may be a positive indicator for recovery post-thrombectomy.
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Background: During the hospital-to-home transition, stroke survivors and their caregivers face a significant lack of support and information which impacts their psychosocial recovery. We aimed to co-design a program combining individual support by a trained case-manager (dedicated professional providing individual support) and an online information platform to address needs of stroke survivors and caregivers.

Methods: A two-step methodology was used.

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Background: Adherence to post-stroke secondary prevention medications mitigates recurrence risk. This study aimed to measure adherence to secondary prevention medications during 3 years post-ischemic stroke/transient ischemic attack, using prescription and dispensing data, and identify factors associated with suboptimal adherence.

Methods: This multicenter, prospective, cohort study involved patients from the STROKE 69 cohort, which included all consecutive patients with suspected acute stroke admitted between November 2015 and December 2016 to any emergency department or stroke center in the Rhône area in France.

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Introduction: To investigate the relationship between collaterals and blood-brain barrier (BBB) permeability on pre-treatment MRI in a cohort of acute ischemic stroke (AIS) patients treated with thrombectomy.

Methods: We conducted a retrospective analysis of the HIBISCUS-STROKE cohort, a single-center observational study that enrolled patients treated with thrombectomy from 2016 to 2022. Dynamic-susceptibility MRIs were post-processed to generate K2 maps with arrival-time correction, which were co-registered with apparent diffusion coefficient (ADC) maps.

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Article Synopsis
  • Stroke survivors and their caregivers often struggle with a lack of support and information after discharge, leading to increased psychosocial challenges, which could potentially be addressed by online resources.
  • A review identified eleven studies that evaluated ten different online resources aimed at improving psychosocial health for both stroke survivors and their caregivers, highlighting a mix of websites, an app, and a forum.
  • While some resources effectively reduced depressive symptoms, there is still a need for more comprehensive research on the impact of these online interventions on long-term psychosocial recovery in stroke patients and their caregivers.
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