Publications by authors named "L Demir"

Preterm birth is a leading risk factor for atypicalities in cognitive and sensory processing, but it is unclear how prematurity impacts circuits that support these functions. To address this, we trained adult mice born a day early (preterm mice) on a visual discrimination task and found that they commit more errors and fail to achieve high levels of performance. Using , we found that the neurons in the primary visual cortex (V1) and the V1-projecting prefrontal anterior cingulate cortex (ACC) are hyper-responsive to the reward, reminiscent of cue processing in adolescence.

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Bloody coin is a dangerous game that is frequently played among children and is becoming increasingly widespread. In this article, we aimed to present a patient treated for a serious hand infection requiring hospitalization due to this game. A 13-year-old girl was consulted to our plastic, reconstructive and aesthetic surgery clinic with a large erythema on the dorsum of her right hand.

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Article Synopsis
  • Preterm birth is linked to cognitive and sensory processing issues, but the underlying neural mechanisms remain unclear, prompting researchers to study preterm mice and their performance on visual tasks.
  • The study reveals that preterm mice struggle with visual discrimination, displaying hyper-responsive neurons related to rewards while showing impaired activity in prefrontal circuits during errors.
  • Environmental enrichment intended to enhance sensory development did not improve performance in preterm mice, indicating that early interventions may have limited effectiveness in addressing cognitive deficits associated with preterm birth.
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Article Synopsis
  • - The study aimed to evaluate the effectiveness of combining hyperbaric oxygen therapy (HBOT) and topical haemoglobin spray in treating difficult diabetic foot ulcers (DFUs) with significant slough or necrosis.
  • - Patients receiving the combo treatment (oxygen group) showed a higher healing rate of 85.7% compared to 52.4% in the control group after 16 weeks, although the initial wound severity scores were similar.
  • - The findings suggest that this combined therapy enhances wound oxygenation, addressing hypoxia and promoting healing more effectively than standard wound care alone.
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