Publications by authors named "L Delugin"
Article Synopsis
- The French health authorities established guidelines for "good transfusion practices," but there is limited guidance for managing transfusions in patients who have undergone allogeneic hematopoietic stem transplantation (allo-HCT).
- A workshop aimed to standardize transfusion practices for this patient group where recommendations are lacking.
- Key recommendations include conducting extended blood cell phenotyping before transplantation, monitoring antibody levels, and assessing chimerism at specific intervals post-transplant to adjust transfusion strategies as needed.
Unlabelled: Brittany is a low prevalence region for hemoglobinopathies. Despite of that, the number of patients is increasing each year. In 2013, 140 patients were known at the EFS Bretagne, and medical consultations are growing for 50% each year since 2011.
View Article and Find Full Text PDFUnlabelled: Antitetanus antibodies titration is carried out by French National Blood Services (FNBSs) with the aim of seeking donors whose title of antibodies are greater or equal to 8 IU/ml. Different kits are used: ELISA antitetanus toxoid IgG (The Binding Site), ELISAT (Diagast), tetanus toxoid IgG ELISA (Diamed), ELISA IgG tetanus (Ingen). As the results obtained using these different reagents show some discrepancies with the control results carried out by the Laboratoire Français des Biotechnologies (LFB), it appeared necessary to harmonize the selection practices.
View Article and Find Full Text PDF1. Glibenclamide, a sulphonylurea widely used for the treatment of non-insulin-dependent diabetes mellitus, has been shown to inhibit the activities of various ATP-binding cassette (ABC) transporters. In the present study, its effects towards multidrug resistance protein 1 (MRP1), an ABC efflux pump conferring multidrug resistance and handling organic anions, were investigated.
View Article and Find Full Text PDF