Publications by authors named "L Delesie"
Article Synopsis
- Vaccines need to encourage mucosal immunity to effectively prevent infection by respiratory viruses, but the impact of current mRNA COVID-19 vaccines on this type of immunity is not well understood.
- A study with 183 individuals revealed that repeated mRNA booster vaccinations significantly increased neutralizing antibodies in nasal secretions, suggesting a connection between nasal and serum antibody levels.
- Further research in a mouse model indicated that the antibodies linked to mucosal immunity come from the spleen and bone marrow and can migrate from the bloodstream to the respiratory mucosa, providing insights for future vaccine development.
Background: Poor subjective sleep quality, depressive symptoms and fatigue occur frequently in postpartum. However, the dynamics of their respective associations from prepartum throughout the maternity period in function of baby feeding method have not been fully elucidated.
Methods: Prospective, longitudinal study using validated questionnaires probing for sleep quality, insomnia, fatigue and depressive symptoms at 35-37 weeks of gestation and at 2, 8 and 12 weeks postpartum in the obstetric departments of two Flemish hospitals.
Objectives: This study aimed to assess the efficacy and safety of 300 mg camostat mesylate three times daily in a fasted state to treat early phase COVID-19 in an ambulatory setting.
Methods: We conducted a phase II randomized controlled trial in symptomatic (maximum 5 days) and asymptomatic patients with confirmed COVID-19 infection. Patients were randomly assigned in a 2:1 ratio to receive either camostat mesylate or a placebo.
Slow Wave Sleep of Elite and Nonelite Gymnasts Is Influenced by Weekly Training Hours, Not by Fitness Level.
Int J Sports Physiol Perform
January 2022
Purpose: This study aimed to determine the influencing factors of potential differences in sleep architecture between elite (EG) and nonelite (NEG) female artistic gymnasts.
Methods: Twelve EG (15.1 [1.
The aim of this study was to determine the frequency of upper respiratory tract symptoms (URS) in elite female gymnasts during a training season. In addition, we aimed to observe the extent to which salivary immunoglobulin A (sIgA) is associated with URS in these athletes, including potential effects of the season and timing of sample collection. Over one year, 18 elite female gymnasts completed URS and fatigue questionnaires weekly and provided 1 mL of saliva after a minimum 36 h of rest (morning or afternoon) to measure relative sIgA concentration (= mean absolute sIgA value of the week divided by the mean absolute sIgA value of the weeks without URS).
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