Publications by authors named "L De Gennaro"
The aim of the present study is to investigate differences in brain networks modulation during the pre- and post-sleep onset period, both within and between two groups of young and older individuals. Thirty-six healthy elderly and 40 young subjects participated. EEG signals were recorded during pre- and post-sleep onset periods and functional connectivity analysis, specifically focusing on the small world (SW) index, applied to EEG data (i.
View Article and Find Full Text PDFMineralocorticoid receptor antagonists (MRAs) represent one of the cornerstones of treatment for heart failure with reduced ejection fraction. Post-hoc data from the TOPCAT trial, conducted in patients with heart failure mildly reduced or preserved ejection fraction (HFmrEF/HFpEF), suggest the possible clinical benefit of MRAs, particularly for slightly reduced ejection fraction values. The advent of non-steroidal MRAs, including finerenone, seems to represent a turning point in the treatment for HFmrEF/HFpEF.
View Article and Find Full Text PDFArticle Synopsis
- - The study explores how pregnancy-related factors, emotional awareness (alexithymia), and depression impact dream experiences in women during their first trimester, suggesting that dreaming helps with emotional regulation during this sensitive period.
- - 118 pregnant women participated in various questionnaires measuring their dream characteristics, emotional awareness, and depression, revealing that older age, prior pregnancies, and depressive symptoms influenced dream recall and nightmares.
- - Findings indicate that higher alexithymia and depressive symptoms are linked to more frequent and distressing nightmares, suggesting a need for targeted support to improve emotional coping strategies in pregnant women; future studies should look into the content of these nightmares for better understanding.
Background: Early reconstruction of the skull represents the gold standard after resection of bone infiltrating cranial tumors. Customized hydroxyapatite porous ceramics are an excellent option for covering skull bone defects. The authors illustrate the surgical technique and investigate the effectiveness of the "one-step" procedure in terms of aesthetic results and early degree of osteointegration.
View Article and Find Full Text PDFBackground: The Italic Iron Age is characterized by the presence of various ethnic groups partially examined from a genomic perspective. To explore the evolution of Iron Age Italic populations and the genetic impact of Romanization, we focus on the Picenes, one of the most fascinating pre-Roman civilizations, who flourished on the Middle Adriatic side of Central Italy between the 9 and the 3 century BCE, until the Roman colonization.
Results: More than 50 samples are reported, spanning more than 1000 years of history from the Iron Age to Late Antiquity.