Publications by authors named "L Dangers"
Background: Veno-Venous Extracorporeal Membrane Oxygenation (VV-ECMO) is an efficient ventilatory support in patients with refractory Covid-19-related Acute Respiratory Distress Syndrome (ARDS), however the duration of invasive mechanical ventilation (IMV) before ECMO initiation as a contraindication is still controversial. The aim of this study was to investigate the impact of prolonged IMV prior to VV-ECMO in patients suffering from refractory Covid-19-related ARDS.
Methods: This single-center retrospective study included all patients treated with VV-ECMO for refractory Covid-19-related ARDS between January 1, 2020 and May 31, 2022.
Article Synopsis
- Acinetobacter baumannii (Ab) is a significant cause of severe community-acquired pneumonia (CAP) in tropical regions, particularly noted in a study from Réunion University Hospital, where eight cases were reviewed from 2014 to 2022.
- The majority of patients were middle-aged males with a history of smoking and chronic alcohol use, presenting during the rainy season and often experiencing septic shock and severe respiratory distress.
- The mortality rate was high at 62.5%, with all patients initially receiving inappropriate antibiotic treatment; however, Ab isolates were mostly susceptible to several key antibiotics.
Article Synopsis
- Management of dual antiplatelet therapy (DAPT) in VA-ECMO patients post-acute myocardial infarction (AMI) presents challenges, with significant occurrences of severe bleeding and coagulation issues.
- A study analyzed 176 post-AMI patients on VA-ECMO, finding nearly 39% experienced severe bleeding and a high mortality rate of 49%.
- Factors such as female sex, duration on ECMO, and certain biomarkers were linked to an increased risk of severe bleeding, which led to the discontinuation of antiplatelet therapy in one-third of the cases.
Article Synopsis
- The study investigates how increasing the sweep gas flow in venoarterial ECMO patients with cardiogenic shock affects dyspnea.
- Nonintubated patients with significant dyspnea were assessed while sweep gas flow was increased, showing a marked reduction in dyspnea levels.
- Results indicated that higher sweep gas flow led to significant decreases in both the sensory and emotional aspects of dyspnea and reduced respiratory muscle activity, suggesting a strong relationship between gas flow and dyspnea relief.
Objectives: Venoarterial extracorporeal membrane oxygenation (VA-ECMO) requires considerable human and financial resources. Few studies have focused on early mortality (ie, occurring within 72 hours after VA-ECMO implantation). The objective of this study was to establish a prognosis score-the IMPACT score (prediction of early mortality associated with VA-ECMO using preimplantation characteristics)-by determining the risk factors associated with early mortality.
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