[Experience with the organization of a pathological anatomy laboratory in a heart surgery center].

Some specific features should be taken into consideration when organizing the laboratory of pathology in the cardiosurgical centre: 1) the heart should be opened according to the modified van Pragh method; 2) heart fixation in the Brodie's liquid allowing to retain its almost natural colour, consistency, volume and shape; 3) coronary arteries filling with lead carbonate and gelatin; 4) combination of methods of both pathology and surgical anatomy; 5) investigation of the brain in the vacuum in all clinical cases of the brain coma for the diagnosis of brain artery air embolism; 6) anatomical examination of the heart conductive system; 7) formation of the automatized pathology archives; 8) transmission electron microscopy of the intraoperative heart biopsies; 9) a new method of a quantitative assessment of the lung hypertension by the investigation of lung biopsies in patients with congenital heart malformation to make a conclusion on the feasibility of operation; 10) macroscopical heart analysis at the first stage of morphological investigation.

[Characteristic features of the pathological anatomy and involvement of the myocardium in anomalous branching of the left coronary artery from the pulmonary trunk (Clinico-anatomical comparisons)].

Pathologic, clinical and anatomical correlations are presented for left ventricular affection in abnormal origin of the left coronary artery from the pulmonary trunk. It was revealed that there is a complex of critical factors essential for survival of patients and clinical pattern of the defect including the degree of manifestation of intercoronary collateral circulation, specificity of myocardial left ventricular ischemic impairment and that of mitral structure. Clinical and anatomical comparisons are drawn between the degree of affection of the left ventricular myocardium and its functional capacity.

[What is anomalous departure of the aorta and pulmonary artery from the right ventricle?].

Available literature data on terminological and anatomical definition of congenital combined valvular disease--anomalous right ventricular origin of the aorta and pulmonary artery--are reviewed. Not a single report analysed permitted an objective precise structural outline of the disease. The causes of this situation are elicited.

[Architectonic characteristics of the heart ventricles in a perimembranous defect of the interventricular septum].

The results of quantitative morphological macro-, micro-, and ultrastructural (myocardial biopsies) studies of the ventricles with perimembranous septal defect in 135 infants under the age of one year have been compared. In newborns there appeared ventricular myocardial hyperplasia and low absolute and relative values of all the myocardial parameters versus normal control. At the age of 3 months the parameters were similar to or above the control ones exceeding them considerably by the age of 10-12 months.