This work is experimental and devoted to the study of functional activity of the pineal gland. The influence of the main biologically active substances (serotonin, melatonin, mexamin) produced by the epiphysis, on the hypothalamo-hypophysial structures was studied; results pointed to the significant role played by the epiphysis in the neuroendocrine regulation system.
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November 1977
Melatonin content in the epiphysis, serotonin, noradrenaline, dopamine-in the hypothalamus, gonadotropins--in the hypophysis of rats was studied under normal conditions and following ovariectomy; regularly of the estral cycle phases was studied as well. Two series of experiments were conducted on 120 rats with regular estral cycles. The animals were divided into groups according to the estral cycle phase.
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