The impact of highly effective modulator therapy on sinusitis and dysosmia in young children with cystic fibrosis: a prospective study protocol.

Background: Chronic rhinosinusitis (CRS) and olfactory dysfunction (OD) are prevalent disease complications in people with cystic fibrosis. These understudied comorbidities significantly impact quality of life. The impact of highly effective modulator therapy (HEMT) in young children with cystic fibrosis (YCwCF) on these disease complications is unknown.

High genomic connectivity within Anatoma at hydrothermal vents along the Central and Southeast Indian Ridge.

Hydrothermal vents are ecosystems inhabited by a highly specialized fauna. To date, more than 30 gastropod species have been recorded from vent fields along the Central and Southeast Indian Ridge and all of them are assumed to be vent-endemic. During the INDEX project, 701 representatives of the genus Anatoma (Mollusca: Vetigastropoda) were sampled from six abyssal hydrothermal vent fields.

Analysis of selected nutrients and contaminants in fish oil supplements for dogs.

Fish oil supplements for dogs are used therapeutically for various clinical conditions. However, products may be variable in quality, potency, and stability. The objective of this study was to analyze eleven canine fish oil supplements from two time points (2010 and 2021) for the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), polychlorinated biphenyl (PCB) arochlors, minerals, and vitamins A and D, and to compare their compositions to label claims.

Toward the Bayesian brain: a generative model of information transmission by vestibular sensory neurons.

The relative accessibility and simplicity of vestibular sensing and vestibular-driven control of head and eye movements has made the vestibular system an attractive subject to experimenters and theoreticians interested in developing realistic quantitative models of how brains gather and interpret sense data and use it to guide behavior. Head stabilization and eye counter-rotation driven by vestibular sensory input in response to rotational perturbations represent natural, ecologically important behaviors that can be reproduced in the laboratory and analyzed using relatively simple mathematical models. Models drawn from dynamical systems and control theory have previously been used to analyze the behavior of vestibular sensory neurons.

A feasibility study on the use of near infrared spectroscopy to predict fatty acid concentration in intact black soldier fly reared in different waste streams.

The black soldier fly larvae (BSFL) are well known to utilise a wide variety of organic waste streams, delivering a product rich in protein (30-50%) and lipids (15-49%) and other micronutrients. The objective of this study was to evaluate the ability of NIR spectroscopy combined with chemometrics to predict the concentration of fatty acids in BSFL reared in different commercial waste streams. Intact BSFL samples were analysed using a bench top NIR instrument where calibration models for fatty acids were developed using partial least squares (PLS) regression.