Publications by authors named "L D Estkowski"

Deep learning (DL) reconstruction techniques to improve MR image quality are becoming commercially available with the hope that they will be applicable to multiple imaging application sites and acquisition protocols. However, before clinical implementation, these methods must be validated for specific use cases. In this work, the quality of standard-of-care (SOC) T2w and a high-spatial-resolution (HR) imaging of the breast were assessed both with and without prototype DL reconstruction.

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Graphically prescribed patient-specific imaging volumes and local pre-scan volumes are routinely placed by MRI technologists to optimize image quality. However, manual placement of these volumes by MR technologists is time-consuming, tedious, and subject to intra- and inter-operator variability. Resolving these bottlenecks is critical with the rise in abbreviated breast MRI exams for screening purposes.

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Purpose: To assess the effects of cardiovascular-induced motion on conventional DWI of the pancreas and to evaluate motion-robust DWI methods in a motion phantom and healthy volunteers.

Methods: 3T DWI was acquired using standard monopolar and motion-compensated gradient waveforms, including in an anatomically accurate pancreas phantom with controllable compressive motion and healthy volunteers (n = 8, 10). In volunteers, highly controlled single-slice DWI using breath-holding and cardiac gating and whole-pancreas respiratory-triggered DWI were acquired.

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Objectives: To describe and compare off-label use and cardiovascular (CV) adverse effects of dexmedetomidine in neonates and infants in the pediatric intensive care unit (PICU).

Methods: Patients younger than 12 months with corrected gestational ages of at least 37 weeks who were receiving continuous infusion of dexmedetomidine at a tertiary pediatric referral center between October 2007 and August 2012 were assessed retrospectively. Patients were excluded if dexmedetomidine was used for procedural sedation, postoperative CV surgery, or if postanesthesia infusion weaning orders existed at the time of PICU admission.

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Objective: The objective of our study was to evaluate a new 3D fast spoiled gradient-recalled echo (FSPGR) sequence referred to as modified liver acceleration volume acquisition (LAVA) for high-resolution gadolinium-enhanced dual arterial phase liver MRI and to determine the effect of this technique on the timing of the contrast bolus and lesion detection.

Materials And Methods: Gadolinium-enhanced dual arterial phase liver MRI was performed in 109 patients using a modified LAVA sequence that supports adaptive 2D centric view ordering, efficient 2D autocalibrated acceleration, and partial-Fourier to achieve faster scan times while maintaining the same slice thickness, resolution, and coverage as single-phase imaging. After a fixed 20-second scan delay, a modified LAVA acquisition required a single 24- to 26-second breath-hold for two arterial phases with 56-60 slices per pass.

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