Publications by authors named "L D Dhinesh Babu"
Despite advancements in detection and treatment, tuberculosis (TB), an infectious illness caused by the Mycobacterium TB bacteria, continues to pose a serious threat to world health. The TB diagnosis phase includes a patient's medical history, physical examination, chest X-rays, and laboratory procedures, such as molecular testing and sputum culture. In artificial intelligence (AI), machine learning (ML) is an advanced study of statistical algorithms that can learn from historical data and generalize the results to unseen data.
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- Lymphatic filariasis (LF) is a neglected tropical disease caused by mosquito-borne parasites affecting 51 million people globally, with mass drug administration recommended by WHO in endemic areas like coastal Kenya.
- In 2022, a study collected over 18,000 mosquitoes from LF-endemic counties in Kenya to analyze infection rates of Wuchereria bancrofti, utilizing molecular xenomonitoring methods.
- Results indicated higher infection rates in Kilifi County at 35.4% compared to 5.3% in Taita Taveta, with major vectors identified including An. rivulorum, An. funestus, and An. arabiensis, highlighting the need for targeted interventions.
Ru(II)-complexes have been recognised as promising in treating cancer. However, targeted delivery is an important facet to augment the efficiency of drugs. Consequently, this article portrays the construction of biotinylated-MWCNTs as an SMVT-guided nano-platform for the precise delivery of our previously-developed potent Ru(II)-scaffold, making it more effective against MCF-7 cells.
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- The study aimed to assess how different dosing regimens of ivermectin affect the survival of malaria vectors (mosquitoes) and their potential to reduce malaria transmission.
- An open-label randomized control trial was conducted in Kenya with 36 participants, comparing a single dose of ivermectin, a 3-day regimen of ivermectin, albendazole, and a control group with no treatment.
- Results indicated that both ivermectin regimens significantly impacted mosquito survival within the first week, but the single dose proved to be more effective over a 10-day period compared to the multi-day regimen.
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- Uncorrected refractive error is a major cause of blindness, and self-refraction methods, including self-adjustable eyeglasses, are becoming popular for correcting these errors; this study aimed to compare outcomes of Self-refraction (SR) eyeglasses with Cycloplegic subjective Refraction (CSR).* -
- The study involved 59 participants aged 18-30, with specific refractive errors, and excluded those with certain eye conditions; participants estimated their refractive error using DialVision eyeglasses followed by a CSR assessment by a single examiner.* -
- Results showed significant differences in visual acuity, with SR yielding a mean acuity of 0.14 compared to CSR's 0.002