A comprehensive review of massive transfusion and major hemorrhage protocols: origins, core principles and practical implementation.

Until the beginning of the century, bleeding management was similar in elective surgeries or exsanguination scenarios: clotting tests were used to guide blood product orders and, while awaiting these results, an aggressive resuscitation with crystalloids was recommended. The high mortality rate in severe hemorrhages managed with this strategy endorsed the need for a special resuscitation plan. As a result, modifications were recommended to develop a new clinical approach to these patients, called "Damage Control Resuscitation".

Luminescent Thermometer Based on a Praseodymium(iii) Cyanide-Based Metal-Organic Framework.

Trivalent lanthanide ions have emerged as promising candidates for precise and remote temperature sensing. Among them, Pr-based luminescent thermometers remain underexplored, particularly those operating in the near-infrared (NIR) spectral region. This work presents the synthesis and thorough characterization of a novel Pr-based coordination polymer, {[PrPt(CN)(4,4'-bpyO)(HO)]·4HO} (), as a rare example of Pr luminescent thermometry.

Clinical and sensitization profile in peach allergy due to LTP sensitization.

Background: Lipid transfer proteins (LTP) are associated with a wide range of severity of allergic reactions. However, the risk factors associated with this severity are not fully understood.

Objectives: To describe the clinical characteristics of peach-allergic patients due to LTP sensitization and analyze the relationship between the severity of the reactions and patients' sensitization profiles.

Successful implementation of a patient blood management programme in a lower middle-income state.

Background And Objectives: Transfusions are common, but their use is decreasing in some countries as a result of increased risk awareness and the implementation of patient blood management (PBM), an evidence-based approach to optimize patient outcomes. This study aimed to detail the implementation of PBM in a Brazilian state and its impact on transfusion rates and associated costs.

Materials And Methods: The PBM implementation involved several strategies: medical education, haematology consultation services, provision of intravenous iron and other medications, establishment of PBM and perioperative anaemia clinics, cell salvage and acute normovolaemic haemodilution, anaemia reference laboratories and rotational thromboelastometry.

Rethinking Assumptions: Assessing the Impact of Strong Magnetic Fields on Luminescence Thermometry.

Luminescence (nano)thermometry has exploded in popularity, offering a remote detection way to measure temperature across diverse fields like nanomedicine, microelectronics, catalysis, and plasmonics. A key advantage is its supposed immunity to strong electromagnetic fields, a crucial feature in many environments. However, this assumption lacks comprehensive experimental verification as most of the proposed luminescent thermometers rely on magnetic ions, such as lanthanides.