Publications by authors named "L D'Andrea Petrelli"

Article Synopsis
  • Researchers have focused on fascias in recent years, particularly their anatomy and related diseases, using advanced imaging techniques like ultrasound (US) and MRI for better insights.
  • This study aimed to evaluate the effectiveness of using US-guided core needle biopsy to sample fascial tissues from various regions in cadavers, assessing visibility, accuracy, and the reliability of needle placements.
  • Results showed that US-guided biopsies are consistent and reliable, successfully capturing high-quality tissue samples, which could aid in diagnosing conditions like eosinophilic fasciitis.
View Article and Find Full Text PDF

Peripheral nerve injury (PNI) is a complex clinical challenge resulting in functional disability. Neurological recovery does not always ensure functional recovery, as extracellular matrix (ECM) alterations affect muscle function. This study evaluates hyaluronan (HA) and collagen concentration in the gastrocnemius muscle and thoracolumbar fascia (TLF) in unilateral lower limb PNI rats to explore systemic ECM alterations following PNI and their impacts on functional recovery.

View Article and Find Full Text PDF
Article Synopsis
  • Dupuytren's disease is a chronic condition affecting the hand's palmar fascia, with a recurrence rate of 20-40% after surgery, prompting this study to explore changes in specific fibres related to the disease's progression.
  • Researchers analyzed twelve human samples to examine blood and lymphatic vessel changes, collagen distribution, and inflammation through various advanced laboratory techniques, focusing on stages classified by Tubiana.
  • Findings indicated a significant increase in arterial vascularization and a decrease in lymphatic drainage as the disease progressed, along with inflammatory responses that shifted towards collagen synthesis after the initial inflammatory stages, highlighting the importance of understanding these changes for better treatment outcomes.
View Article and Find Full Text PDF

Muscles and fasciae are mutually connected and are influenced by force transmission. However, the anatomical connectivity and histological features of these structures remain unclear. The aim of this study was to assess the evidence for connection between muscles and deep/muscular fasciae.

View Article and Find Full Text PDF

The suprapatellar fat pad is an adipose tissue located in the anterior knee whose role in osteoarthritis is still debated. Considering that anatomy drives function, the aim of this histotopographic study was to investigate the specific morphological features of the suprapatellar fat pad versus the infrapatellar fat pad in the absence of osteoarthritis, for a broad comparative analysis. Suprapatellar fat pad and infrapatellar fat pad tissue samples (n = 10/group) underwent microscopical/immunohistochemical staining and transmission electron microscopy analysis; thus, tissue-specific characteristics (i.

View Article and Find Full Text PDF