Publications by authors named "L Culliford"
Background: The ComFluCOV trial tested the safety and immunogenicity of COVID-19 and influenza vaccines co-administration. Binding and functional SARS-CoV2 anti-spike responses were measured using assays developed in response to the COVID-19 pandemic. The three assays used to measure the immunogenicity outcomes are reported here and their performance compared to inform future vaccine development.
View Article and Find Full Text PDFObjective: To determine the feasibility of conducting a randomised controlled trial (RCT) to evaluate a prehabilitation programme for frail patients undergoing total hip replacement (THR) or total knee replacement (TKR).
Design: Randomised feasibility study with embedded qualitative work.
Setting: Three National Health Service hospitals.
Article Synopsis
- * The RADICAL trial is a randomized controlled study involving 250 adults, comparing RFD to a placebo, with the primary goal of assessing pain severity three months after the procedure.
- * The study will also evaluate various outcomes such as disability and quality of life up to two years later and aims to provide better economic insights into RFD's effectiveness from the NHS's perspective.
This study formed part of a diagnostic test accuracy study to quantify the ability of three index home monitoring (HM) tests (one paper-based and two digital tests) to identify reactivation in Neovascular age-related macular degeneration (nAMD). The aim of the study was to investigate views about acceptability and explore adherence to weekly HM. Semi-structured interviews were held with 98 patients, family members, and healthcare professionals.
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