Publications by authors named "L Cudillo"
Management of latent tuberculosis infection (LTBI) in adult patients with newly diagnosed acute leukemia: results of a survey among Italian centers belonging to SEIFEM (Sorveglianza Epidemiologica Infezioni nelle Emopatie) group.
Ann Hematol
December 2024
Article Synopsis
- COVID-19 continues to significantly impact patients with chronic lymphocytic leukemia (CLL), with a study analyzing 256 CLL patients showing a high case fatality rate of 30.1%.
- Most patients were symptomatic and required hospitalization, with a considerable portion having received recent therapy for their CLL.
- Factors like male sex, age over 70, recent treatment, and severity of COVID-19 were found to be strong predictors of poor survival outcomes among these patients.
Elderly patients represent the most challenging and hard-to-treat patient population due to dismal characteristics of the disease, such as secondary-acute myeloid leukemia (AML), enrichment of unfavorable molecular genes () and comorbidities. We conducted a multicentric retrospective study to evaluate activity and safety in a real-life setting of hypomethylating drugs (HMAs) in patients older than 75 years with AML. Between September 2010 and December 2021, 220 patients were treated, 164 (74.
View Article and Find Full Text PDFIntroduction: Bone involvement in Multiple Myeloma results from increased osteoclast formation and activity that occurs in proximity to myeloma cells. The role of Alkaline Phosphatse (ALP) in this process and the diagnostic significance of plasma levels in patients with MM are unclear.
Aim: To compare plasma ALP levels in patients with MM and solid cancers and metastatic lesions to the bone.