Publications by authors named "L Cucco"

Article Synopsis
  • Actinobacillus pleuropneumoniae causes porcine pleuropneumonia, a serious lung infection in pigs, and is typically managed using antibiotics like phenicols.
  • This study identifies three florfenicol-resistant isolates of A. pleuropneumoniae from Italian pig farms, all harboring the floR gene and showing varying susceptibility levels.
  • Whole genome sequencing revealed moderate virulence traits and the presence of a novel plasmid, pAp-floR, which is closely related to another plasmid and shows stability without selective pressure, emphasizing the need to monitor resistance in this bacterium.
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Article Synopsis
  • The study aimed to investigate the global spread of a specific linezolid-resistant Enterococcus faecalis strain (ST476), focusing on its genetic characteristics and distribution.
  • Researchers analyzed genomes from the NCBI database and found 66 isolates from 15 different countries, suggesting a wide geographical presence of this resistant strain primarily in humans and animals.
  • The findings indicate that the optrA gene, responsible for resistance, is closely associated with transposon Tn6674 and that the emergence of this clone poses significant public health risks, highlighting the need for a coordinated One Health strategy to manage its spread.
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Background: Streptococcus suis is an important pig pathogen and an emerging zoonotic agent. In a previous study, we described a high proportion of penicillin-resistant serotype 9 S. suis (SS9) isolates on pig farms in Italy.

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The spread of extended-spectrum β-lactamase (ESBL)-producing is a major public health issue. Bivalves are filter-feeder animals capable of bioaccumulating the microorganisms present in water. This physiological characteristic makes them both good indicators of environmental contamination and possible carriers of pathogenic bacteria, including those resistant to antimicrobials.

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