[Clinico-bacteriological correlations in necrotizing fasciitis].

The authors analyze under the aspect of data offered by medical literature, the clinical aspects and occurrence of the microbial flora in the necrotizing fasciitis. The clinical symptoms are presented in correlation with the aerobic, anaerobic and mixed bacterial specificity with the purpose of a suitable antibacterial therapy. Further, there are presented certain aspects of cutaneous "bubbly" lesions connected with the microbial flora in the NF.

[Interference of chloramphenicol with some cytoplasmatic enzyme systems].

The activity of alkaline phosphatase was determined in a lot of Wistar white rats which had received during 8 days therapeutical doses of chloramphenicol hemisuccinate, the enzyme being investigated in the circulating granulocytes and the liver. In the neutrophil granulocytes evidence was found of a marked decrease in alkaline phosphatase activity (40% presented a positive activity in the injected animals as against 70% in the controls). In the liver the histochemical test used did not allow for a discrimination between the experimental and control animals.