Publications by authors named "L Cristobal"

Article Synopsis
  • Precise identification of nerve fascicles is crucial for certain surgeries on peripheral nerves, with bipolar nerve stimulation preferred, but many still use handheld monopolar stimulators.
  • The study presents a new technique for monopolar stimulation, where both the anode and cathode are placed on the same nerve fascicle to enhance specificity.
  • Two surgical cases demonstrated that this modified method allowed for better selection of nerve fascicles, resulting in successful outcomes without unexpected complications.
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Background: Transfer of the fascicle carrying the flexor carpi ulnaris (FCU) branch of the ulnar nerve (UN) to the biceps/brachialis muscle branch of the musculocutaneous nerve (Oberlin's procedure), is a mainstay technique for elbow flexion restoration in patients with upper brachial plexus injury. Despite its widespread use, there are few studies regarding the anatomic location of the donor fascicle for Oberlin's procedure. Our report aims to analyze the anatomical variability of this fascicle within the UN, while obtaining quantifiable, objective data with intraoperative neuromonitoring (IONM) for donor fascicle selection.

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Article Synopsis
  • - Regenerative Peripheral Nerve Interfaces (RPNIs) utilize nerve grafts to enhance electrical signaling in peripheral nerves, and this study reviewed existing research on RPNIs using animal models from 1970 to 2023.
  • - A total of 104 articles on RPNIs were analyzed, with 35 specifically focusing on animal studies, predominantly using mice (91%) and a smaller number using macaques (9%).
  • - Key findings showed significant axonal regeneration and improved blood vessel formation, with RPNIs effectively able to detect and amplify nerve signals, indicating promising long-term performance that can guide future research.
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Article Synopsis
  • A study was conducted on early-stage breast cancer patients without diabetes who received dexamethasone alongside taxane chemotherapy from August 2017 to December 2019.
  • The research found that 67% of these patients experienced steroid-induced hyperglycemia (SIH), with significant glycemic fluctuations in those reaching glucose levels above 200 mg/dL.
  • Non-Hispanic White patients had a notably higher risk for developing SIH, and over 90% of patients saw their hyperglycemia resolve after treatment, with only a small number remaining hyperglycemic post-treatment.
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Lymphedema is a chronic disease with a high incidence in our society. In this paper, we present a review with the latest advances in imaging techniques and surgical reconstructive treatment of lymphedema (lymphovenous anastomosis, vascularized lymph node transfer, and prophylactic lymphedema surgery). In addition, a protocol is established based on a multidisciplinary team (composed of physiatrists, plastic surgeons, radiologists and nuclear medicine radiologists) to optimize the treatment of these patients.

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