Identifying high occurrence areas of hospitalization and mortality from respiratory diseases in the Brazilian Legal Amazon: a space-time analysis.

Respiratory diseases pose a significant threat to the health of the Brazilian population, ranking among the leading causes of hospitalizations and deaths in the country. The most impacted demographics are children, adolescents, and older adults, who respectively have the highest rates of hospitalizations and deaths. An exploratory ecological study was conducted to assess the spatio-temporal distribution of hospitalizations and deaths due to respiratory diseases among children, adolescents, and older adults residing in municipalities in the Brazilian Legal Amazon.

A proof-of-concept study examining a health communication intervention to reduce cannabis misuse among college students.

Objective: A growing number of U.S. states have legalized cannabis for people 21 and older, but cannabis use and misuse can negatively impact college students' health and academic achievements.

Interleukin-12 treatment reduces tumor growth and modulates the expression of CASKA and MIR-203 in athymic mice bearing tumors induced by the HGC-27 gastric cancer cell line.

Gastric cancer (GC) is one of the most common malignant tumors in the digestive system and due to its poor prognosis, there is an increase in the demand for more effective anticancer therapies. Interleukins are potential anticancer agents which can modulate expression of cancer related genes and have therapeutic effects. Interleukin 12 (IL-12) exhibits potent anti-tumor, anti-angiogenic and anti-metastatic activities and represents the ideal candidate for tumor immunotherapy, due to its ability to activate both innate and adaptive immunities.