Publications by authors named "L Costagliola"
Article Synopsis
- * Out of 113 cases, the majority underwent surgical resection; about 40% received chemotherapy, with lymphadenectomy linked to better survival outcomes.
- * Findings indicate that patients typically present in their 50s, with early-stage cases; however, factors like advanced stage and higher mitotic counts negatively impact survival, suggesting the need for a standardized international registry for better data on diagnosis and treatment.
The enzyme cyclooxygenase 2 is an inducible enzyme expressed at sites of inflammation and in a variety of malignant solid tumors such as endometrial cancer (EC). In EC patients, its over-expression is correlated with progressive disease and poor prognosis. The expression is encoded by a polymorphic gene, called PTGS2.
View Article and Find Full Text PDFAims: To evaluate feasibility and effectiveness on short-term blood glucose control of using glycaemic load counting (GLC) versus carbohydrate counting (CC) for prandial insulin dosing in patients with type 1 diabetes (T1D).
Methods: Nine T1D patients on insulin pump, aged 26-58 years, HbA1c 7.7 ± 0.
The aim of the study was to evaluate the effects of a supervised physical training added to a healthy diet-rich in either carbohydrate and fibre (CHO/fibre) or monounsaturated fatty acids (MUFA)-on postprandial dyslipidaemia, an independent cardiovascular risk factor particularly relevant in type 2 diabetes (T2D). Participants were forty-five overweight/obese subjects with T2D, of both genders, in good blood glucose control with diet or diet+metformin, with normal fasting plasma lipids. According to a parallel groups 2 × 2 factorial design, participants were randomized to an 8-week isoenergetic intervention with a CHO/fibre or a MUFA diet, with or without a supervised low-volume aerobic training programme.
View Article and Find Full Text PDF