Publications by authors named "L Cosenza"
: Cellular biobanks are of great interest for performing studies finalized in the development of personalized approaches for genetic diseases, including β-thalassemia and sickle cell disease (SCD), important diseases affecting the hematopoietic system. These inherited genetic diseases are characterized by a global distribution and the need for intensive health care. The aim of this report is to present an update on the composition of a cellular Thal-Biobank, to describe its utilization since 2016, to present data on its application in studies on fetal hemoglobin induction and on gene editing, and to discuss its employment as a "unique tool" during and after the COVID-19 pandemic.
View Article and Find Full Text PDFGlobal COVID-19 vaccination effort faces the challenges of vaccine hesitancy and resistance, rooted in misinformation and institutional distrust. Addressing these barriers with customized messaging is essential, yet the relationship between vaccine hesitancy and other health-seeking behaviors, like COVID-19 testing, has been underexplored. This study assessed COVID-19 vaccine uptake in Southeastern Louisiana across 10 pharmacies and clinics in areas with historically high rates of COVID-19 infection.
View Article and Find Full Text PDFIntroduction: Benign prostatic hyperplasia (BPH) is a prevalent urological condition leading to lower urinary tract symptoms. Minimal invasive surgical treatment (MISTs) such as Rezūm System are emerging aiming to relieve symptoms. We present results from a single centre prospective study.
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- * This study examined how high-intensity exercise affects cardiorespiratory fitness (CRF), gait, and balance by reviewing 25 randomized controlled trials (RCTs) focused on first-stroke adult survivors.
- * Results showed significant improvements in CRF (measured by the Six-Minute Walking Test and peak oxygen uptake), but no major changes in balance and gait tests, indicating the need for more standardized long-term research to improve rehabilitation.
Article Synopsis
- - The study aimed to compare the effects of rectus femoris diagnostic motor nerve blocks (DNB) and botulinum toxin (BoNT-A) injections on unilateral stiff-knee gait in multiple sclerosis patients.
- - Fourteen stable multiple sclerosis patients were assessed before and after interventions, with tests measuring walking ability and disability status, revealing that DNB results helped predict improvements from BoNT-A.
- - Findings indicated that DNB could be particularly useful for patients with lower functional status, as it effectively forecasted improvements in endurance and walking speed, especially with botulinum treatment.