Publications by authors named "L Copeland"
The amylolytic susceptibility of starch-lipid complexes with different forms of crystallites has been studied extensively, but the fermentation properties of these complexes remain little understood. Hence, the fecal fermentation properties of starch-lipid complexes with V-type and V-type crystallites were investigated in the present study. Compared to V-type complexes, fermentation of V-type complexes caused more severe disruption to the crystallites and resulted in greater acid, reducing sugar, and short-chain fatty acids (SCFAs) production.
View Article and Find Full Text PDFObjectives: To examine the acceptability of implementing, trialling and estimating the cost of the Sexual health and healthy relationships for Further Education (SaFE) intervention.
Design: Two-arm repeated cross-sectional pilot cluster randomised controlled trial (cRCT) of SaFE compared with usual practice, including a process evaluation and an economic assessment.
Setting: Eight further education (FE) settings in South Wales and the West of England, UK.
Combined immune checkpoint blockade (ICB) and chemoradiation (CRT) is approved in patients with locally advanced cervical cancer (LACC) but optimal sequencing of CRT and ICB is unknown. NRG-GY017 (NCT03738228) was a randomized phase I trial of atezolizumab (anti-PD-L1) neoadjuvant and concurrent with CRT (Arm A) vs. concurrent with CRT (Arm B) in patients with high-risk node-positive LACC.
View Article and Find Full Text PDFResistant starch (RS) has been shown to modulate intestinal microbiota in animal models in ways that could reduce the effects of dysbiosis-related diseases. However, the mechanism of how this is achieved is not understood. The present study aimed to reveal the mechanism of how RS mitigates dextran sulfate sodium (DSS)-induced colitis in mice by using a starch-lipid complex (RS type 5), with an RS type 2 from high-amylose maize starch as a comparison.
View Article and Find Full Text PDFArticle Synopsis
- Patient portals, like MyChart, are becoming popular in the U.S. healthcare system, but it's unclear how patients feel about using them for research and health-related tasks.
- A survey of 105 patients revealed that nearly all had used MyChart, primarily for checking lab results and messaging their healthcare providers, with less interest in medication details or health education.
- Most participants expressed willingness to engage in research activities through MyChart, such as answering surveys and health assessments, with significant interest in discussing topics like sleep and stress via the portal.