Publications by authors named "L Chylack"
Background: Long-term corticosteroid use may increase cataract risk. The Lens Opacities Classification System (LOCS) III ranked lens opacities as Class 1: 0.5-0.
View Article and Find Full Text PDFBeclomethasone dipropionate (BDP) nasal aerosol has an established efficacy and safety profile for short-term allergic rhinitis (AR) treatment. However, managing perennial AR (PAR) symptoms often requires long-term treatment. This study evaluates efficacy and safety of long-term treatment with BDP nasal aerosol in PAR patients.
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- This study is the first to look at the eye effects of using an intranasal corticosteroid, fluticasone furoate nasal spray (FFNS), over two years in patients with perennial allergic rhinitis (PAR).
- The trial involved 548 patients aged 12 and older and compared the ocular safety of FFNS with a placebo, measuring eye health through various metrics like intraocular pressure and lens opacities.
- Results showed no significant difference in ocular safety between FFNS and placebo, with most patients experiencing no serious eye-related issues, though epistaxis (nosebleeds) was more common among those using the corticosteroid.
The NASA Study of Cataract in Astronauts (NASCA) was designed to measure the impact of exposure to space radiation on progression rates of cortical, nuclear, and posterior subcapsular cataract in U.S. astronauts who have flown in space and comparison groups of astronauts who had not flown in space, and subjects with a history of military aviation.
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