Publications by authors named "L Chougar"

Objective: Spinocerebellar ataxias (SCA) are neurodegenerative diseases with widespread lesions across the central nervous system. Ataxia and spasticity are usually predominant, but patients may also present with parkinsonism. We aimed to characterize substantia nigra pars compacta (SNc) degeneration in SCA2 and 7 using neuromelanin-sensitive imaging.

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Background And Purpose: So-called contrast-induced encephalopathy (CIE) is a rare but worrying condition occurring after cerebral angiography or neuroendovascular interventions using iodine contrast media. This study aimed to compare cerebral iodine concentrations in patients suspected of having CIE after endovascular procedures to those in matched controls.

Methods: This is a retrospective monocentric study of 25 suspected CIE patients in a tertiary care teaching hospital diagnosed from June 2017 to February 2024.

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  • Deep learning is used for medical image segmentation, but it struggles with small training datasets and can produce inaccurate results; anatomical knowledge can help improve this process.
  • A new loss function based on projected pooling introduces soft topological constraints by highlighting smaller parts of the structure to ensure they aren't overlooked during segmentation.
  • When applied to segment the red nucleus in QSM data, this method achieved high accuracy (Dice 89.9%) and minimized topological errors, making it a promising approach for efficient and accurate medical image segmentation.
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  • * It involved 113 patients with diagnoses like Parkinson's disease and progressive supranuclear palsy, analyzing the accuracy of clinical criteria, MRI readings, and a machine-learning algorithm.
  • * Results indicated that MRI visual reading significantly enhanced diagnostic accuracy by 14.3%, and combining it with clinical criteria further improved accuracy to 85.4%, suggesting MRI is beneficial in early diagnoses.
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  • - Thoracic disc herniation is rare, making up less than 1% of spinal herniations, and while often asymptomatic, it can lead to spinal cord ischemia.
  • - A case involving a 43-year-old man showed Brown-Sequard syndrome, where spinal cord ischemia was linked to a thoracic disc extrusion, initially not compressing the cord on MRI.
  • - The patient was treated conservatively, and after a few months, he recovered as the disc extrusion decreased on its own, illustrating the complexities in diagnosis and management of this condition.
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