Publications by authors named "L Chessa"
Article Synopsis
- The European Union is promoting research in healthy aging, particularly through the use of advanced technologies like virtual reality (VR) for cognitive rehabilitation in older adults with Mild Cognitive Impairment (MCI).
- A randomized controlled clinical study will include 30 participants aged 65 and older, evaluating the feasibility and effectiveness of a 3-month immersive VR cognitive remediation program, supervised by health professionals.
- The study will measure outcomes such as quality of life, cognitive functions, and mental health indicators to determine the program's impact on participants.
Background: Antibody-mediated rejection is a significant cause of kidney transplant failure. Recent studies have shown that the MHC class I gene influences the transplantation outcome. However, the role of the primary receptor, NKG2D, has yet to be explored.
View Article and Find Full Text PDFThe Effect of Exposure to SARS-CoV-2 Vaccination and Infection on Humoral and Cellular Immunity in a Cohort of Patients with Immune-Mediated Diseases: A Pilot Study.
Pathogens
June 2024
Immunization against COVID-19 is needed in patients with immune-mediated inflammatory diseases (IMIDs). However, data on long-term immunity kinetics remain scarce. This study aimed to compare the humoral and cellular response to COVID-19 in patients with immune-mediated inflammatory diseases (IMIDs) compared to healthy controls.
View Article and Find Full Text PDFBackground And Aims: We aimed to characterize the epidemiologic and comorbidities profiles of patients with chronic Hepatitis D (CHD) followed in clinical practice in Italy and explored their interferon (IFN) eligibility.
Methods: This was a cross-sectional study of the PITER cohort consisting of consecutive HBsAg-positive patients from 59 centers over the period 2019-2023. Multivariable analysis was performed by logistic regression model.
Article Synopsis
- The study focused on creating a scoring system called the OCA response score (ORS) to predict how individuals with primary biliary cholangitis (PBC) will respond to the treatment using obeticholic acid (OCA).
- Data were collected from two large cohorts in Italy to derive and validate the score, which includes various clinical factors both before and after six months of treatment.
- The scoring system demonstrated good predictive ability for treatment response, which could help healthcare providers customize therapies for patients with PBC more effectively.