Publications by authors named "L Cherni"
Background: Cytochrome P450 is a superfamily of genes generating hemoproteins that metabolize foreign chemicals as well as endogenous compounds, such as steroids. The human CYP2C genes (CYP2C8, CYP2C9, CYP2C18, CYP2C19) cluster on chromosome 10 and metabolize many clinically useful drugs. CYP2C19 and CYP2C9 have been the most studied while CYP2C8 has been studied less frequently.
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- The study explores the genetic structure of eight North African populations, specifically from Tunisia and Libya, using 30 autosomal SNPs to understand their demographic history and genetic diversity.
- Analysis of data from 403 individuals indicates that North Africans have a genetic composition that is intermediate between European and Asian populations, influenced by migration patterns and prehistoric genetic flow.
- Findings reveal that genetic factors, along with demographic, natural, and cultural influences, have contributed to the diverse genetic landscape of North Africa, highlighting its complex history.
We report here the highly ordered restacking of the layered phosphatoantimonic dielectric materials HMSbPO, (where M = Li, Na, K, Rb, Cs and 0 ≤ ≤ 1), from their nanosheets dispersed in colloidal suspension, induced by a simple pH change using alkaline bases. HSbPO aqueous suspensions are some of the rare examples of colloidal suspensions based on 2D materials exhibiting a lamellar liquid crystalline phase. Because the lamellar period can reach several hundred nanometers, the suspensions show vivid structural colors and because these colors are sensitive to various chemicals, the suspensions can be used as sensors.
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- - The study explores the genetic diversity of two specific SNPs (rs713598 and rs1726866) related to bitter taste perception in northern Africa, focusing on a sample of 375 subjects from Tunisia and Libya.
- - The research reveals that a unique haplotype (CA) associated with a specific amino acid (PV) is much rarer globally but is notably more common (6%-15%) in northern Africa, where it appears alongside other prevalent haplotypes.
- - The authors suggest that the CA haplotype could serve as a useful biogeographic marker in forensic studies due to its distinctive frequency patterns in this relatively understudied region.
Population genetic studies of North Asian ethnic groups have focused on genetic variation of sex chromosomes and mitochondria. Studies of the extensive variation available from autosomal variation have appeared infrequently. We focus on relationships among population samples using new North Asia microhaplotype data.
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