Publications by authors named "L Cherian"
Article Synopsis
- The study examines how diet patterns relate to the risk of intracranial atherosclerosis (ICAD) in people with existing hypertension or a history of myocardial infarction.
- A total of 676 older adults were autopsied, and none showed a direct link between overall diet and atherosclerosis, though hypertension was found to increase the risk of ICAD.
- Notably, individuals with a healthier diet (like the MIND or Mediterranean diet) had lower chances of severe ICAD, especially among those with a history of myocardial infarction.
Introduction: Intracranial atherosclerotic disease (ICAD) of the large cerebral arteries, a leading cause of stroke worldwide, is increasingly implicated in cognitive impairment and neurodegeneration among the general population; however, the underlying pathophysiologic mechanisms in this relationship remain unknown.
Methods: In this narrative review, we aim to provide an overview of the epidemiology and pathophysiology of ICAD, the evidence that relates ICAD to neurodegeneration, putative mechanisms, and future research directions. We synthesized available evidence on PubMed up to August 2024.
Lifestyle Factors and Stroke Prevention: From the Individual to the Community.
Curr Neurol Neurosci Rep
October 2024
Purpose Of Review: The overwhelming majority of stroke burden can be prevented through the pillars of lifestyle medicine: diet, exercise, sleep, substance abuse, stress management, and healthy relationships. Among these, diet confers the greatest attributable risk.
Recent Findings: Despite abundant data and integration of lifestyle medicine within major stroke prevention guidelines, several barriers to effective implementation remain.
Background: Managing antineoplastic orders, side effects, and symptoms is a primary role of oncology advanced practice providers (APPs). Antineoplastic management (ANM) is complex because of risk of medication errors, narrow therapeutic range of agents, frequent dose adjustments, and multiple drug regimens.
Objectives: This article describes an academic institution's review of current practice for ANM privileging and employing Plan-Do-Study-Act (PDSA) cycles to develop a revised process relevant to APP practice, addressing efficiency, accessibility, and cost-effectiveness.
Optimizing Surgical Management of Acute Invasive Fungal Sinusitis.
Turk Arch Otorhinolaryngol
December 2023
Objective: Early surgical debridement is vital for favorable outcomes in acute invasive fungal sinusitis (AIFS). Our study aimed to propose guidelines with tailored, conservative surgical procedures based on areas of involvement and evaluate their usefulness in avoiding repeated debridement.
Methods: This retrospective observational study was conducted on 150 AIFS patients operated on with the proposed surgical guidelines from May to June 2021 at a tertiary care hospital.