Good Psychiatric Management of Borderline Personality Disorder and Co-Occurring Autism Spectrum Disorder.

Borderline personality disorder has been estimated to occur among about 4% of those with autism spectrum disorder. This co-occurrence can escalate the challenges of treating either condition separately, and patients often face severe challenges in psychosocial and occupational functioning. Clinicians need guidance to manage a high degree of complexity, using standards of care and a synthesis of what is known so far, to navigate the currently limited armamentarium of clinical tools.

Exploring the Pathways to Diagnosis for Men With Borderline Personality Disorder: A Qualitative Study.

Borderline personality disorder (BPD) is often perceived as being more common in females, since women are more likely to seek help and be diagnosed. However, epidemiological studies have reported no sex differences in community prevalence. The purpose of this study was to learn from the narrative journeys of men who have received a diagnosis of BPD.

Antiretroviral Drugs Impact Autophagy: Opportunities for Drug Repurposing.

Autophagy is an evolutionarily conserved process in which intracellular macromolecules are degraded in a lysosomal-dependent manner. It is central to cellular energy homeostasis and to quality control of intracellular components. A decline in autophagic activity is associated with aging, and contributes to the development of various age-associated pathologies, including cancer.

SaLTy: a novel Lineage Typer.

asymptomatically colonises 30 % of humans but can also cause a range of diseases, which can be fatal. In 2017 . was associated with 20 000 deaths in the USA alone.

mSphere of Influence: Hooray for HaloTag! A novel tool to study autophagy in mammalian cells.

Laura Cheney works at the crossroads of HIV and autophagy, a critical biological process for cellular homeostasis, to understand more completely the pathogenesis of HIV-associated neurocognitive impairment. In this mSphere of Influence article, she reflects on how "A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag" by Willa Wen-You Yim, Hayashi Yamamoto, and Noboru Mizushima (eLife 11:e78923, 2022, https://doi.org/10.