Publications by authors named "L Chavaz"
Article Synopsis
- The main treatment for immune-mediated thrombotic thrombocytopenic purpura (iTTP) in children includes therapeutic plasma exchange (TPE), corticosteroids, and rituximab, while caplacizumab is used for older children and adults, but its use for those under 12 is not officially approved.
- A case study of a 7-year-old girl with iTTP showed successful treatment with caplacizumab after adjusting the dose according to her ADAMTS13 activity, leading to significant clinical improvement and full recovery without major side effects.
- The review of existing literature revealed five cases of iTTP in children under 12 treated with caplacizumab, all showing success and safety,
In this single-center study of 61 allogeneic hematopoietic cell transplant (HCT) recipients receiving letermovir primary cytomegalovirus (CMV) prophylaxis for the first 100 days, we report 23% incidence of clinically significant CMV infection during the first 100 days after letermovir discontinuation, predominately in haploidentical HCT recipients, without any associations with CMV-DNAemia under letermovir.
View Article and Find Full Text PDFPurpose: The aim of this study is to investigate the spectrum of neurological triad improvement in patients with diffuse intrinsic pontine glioma (DIPG) treated by re-irradiation (re-RT) at first progression.
Methods: We carried out a re-analysis of the SIOP-E retrospective DIPG cohort by investigating the clinical benefits after re-RT with a focus on the neurological triad (cranial nerve deficits, ataxia, and long tract signs). Patients were categorized as "responding" or "non-responding" to re-RT.
Object: Preoperative image-based neuronavigation-assisted endoscopy during intracranial procedures is gaining great interest. This study aimed to analyze the precision of navigation-assisted endoscopy according to the navigation setup, the type of optic and its working angulation.
Methods: A custom-made box with four screws was referenced.