Publications by authors named "L Chauke"

Introduction: critical incidents are among the ten leading causes of death and disability worldwide. Improving patient safety is a global priority and one way of achieving this goal is to report and analyse critical incidents. We aimed to establish the incidence, describe the profile, patient outcomes and avoidable factors associated with gynaecological critical incidents in an academic hospital in Johannesburg, South Africa.

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While maternal deaths have declined by a third between 2000 and 2020, approximately 800 women continue to die every day due to pregnancy-related complications. For every woman who dies, many more experience life-debilitating conditions. Most of these deaths occur in low- and middle-income countries (LMICs).

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Objective: The aim of the present study was to review maternal and fetal outcomes in pregnant women with prosthetic heart valves.

Methods: A retrospective record review of pregnant women with prosthetic heart valves on anticoagulation was performed at the Specialist Cardiac Antenatal Clinic, Johannesburg South Africa from 2015 to 2023.

Results: Fifty pregnancies with mechanical heart valves and three with tissue valves, on anticoagulation for comorbid atrial fibrillation were identified.

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Article Synopsis
  • The study investigates the profiles, causes of death, and complications of women who died from gynecological cancers over four years at a tertiary hospital, based on a review of 48 clinical records.
  • Key findings show that the average age of deceased women was 52.7, with a majority being South African, black, and unemployed; common comorbidities included hypertension and HIV.
  • Cancer types primarily included cervical, ovarian, and endometrial cancers, with most women presenting complications like obstructive uropathy and receiving limited palliative or surgical treatments due to advanced disease stages.
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Pregnancy in kidney and liver transplant recipients presents unique challenges and risks for both maternal and fetal health. This article examines the management of pregnancy in kidney and liver transplant recipients, focusing on pre-pregnancy counselling, trimester-specific care, the teratogenic effects of immunosuppressive drugs, and the role of the multidisciplinary team. While South African (SA) data on this topic are limited, the Transplant Pregnancy Registry International has provided valuable insights.

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