Atypical executive functions (EFs) are well-documented in individuals with autism spectrum disorders (ASD) across all ages. However, most research focuses on EFs impairments in school-aged children and older, with less attention to preschool children. Understanding EF deficits in this age group is challenging and underexplored due to limited studies and measurement difficulties.
View Article and Find Full Text PDF: Horseradish ( L.) roots-largely used in traditional medicine for their multiple therapeutic effects-are a rich source of health-promoting phytochemicals. However, their efficacy can be compromised by low chemical stability and poor bioavailability.
View Article and Find Full Text PDFBackground/objectives: Curcumin is well known for its great anti-inflammatory and antioxidant efficacy, representing a potential strategy for the treatment of respiratory disorders. However, several drawbacks, such as chemical instability, poor water solubility and rapid metabolism, result in low bioavailability, limiting its clinical applications. In this study, curcumin nanocrystals were incorporated into mannitol-based microparticles to obtain an inhalable dry powder.
View Article and Find Full Text PDF: Gestural production, a crucial aspect of nonverbal communication, plays a key role in the development of verbal and socio-communicative skills. Delays in gestural development often impede verbal acquisition and social interaction in children with Autism Spectrum Disorder (ASD). Although various interventions for ASD focus on improving socio-communicative abilities, they consistently highlight the importance of integrating gestures to support overall communication development.
View Article and Find Full Text PDFThis study aimed to evaluate the influence of rat strain in expression of autonomic and cardiovascular changes during acute exposure to restraint stress, as well as in habituation of these physiological responses upon repeated exposure to restraint. For this, blood pressure, heart rate (HR) and sympathetically-mediated cutaneous vasoconstriction were assessed in Wistar (control strain), Long-Evans, Holtzman and spontaneously hypertensive (SHR) rats during acute or 10 60-min session of restraint stress. We observed that HR returned faster to baseline values during recovery of the acute session of restraint in Long-Evans and SHR rats in relation to Wistar, thus indicating shorter tachycardia in these strains.
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