Publications by authors named "L Castrodale"
Background: Borealpox virus (BRPV, formerly known as Alaskapox virus) is a zoonotic member of the Orthopoxvirus genus first identified in a person in 2015. In the six patients with infection previously observed BRPV involved mild, self-limiting illness. We report the first fatal BRPV infection in an immunosuppressed patient.
View Article and Find Full Text PDFBackground: American Indian and Alaska Native (AIAN) populations are frequently associated with the highest rates of tuberculosis (TB) disease of any racial/ethnic group in the USA. We systematically investigated variation in patterns and potential drivers of TB epidemiology among geographically distinct AIAN subgroups.
Methods: Using data reported to the National Tuberculosis Surveillance System during 2010-2020, we applied a geographic method of data disaggregation to compare annual TB incidence and the frequency of TB patient characteristics among AIAN persons in Alaska with AIAN persons in other states.
Article Synopsis
- The study examines patients in Alaska with invasive pneumococcal disease (IPD) who also tested positive for SARS-CoV-2 between January 2020 and December 2021, finding 20% of IPD patients had a concurrent COVID-19 infection.
- No significant differences were found in demographics or health conditions between IPD patients with and without SARS-CoV-2; however, a higher mortality rate was observed in those with both infections (16% vs. 4%).
- The research underscores the importance of vaccination for pneumococcal disease and COVID-19, particularly in vulnerable groups such as those experiencing homelessness.
Objective: and are common causes of reported foodborne illness. On August 6, 2021, the Alaska Division of Public Health identified a multipathogen gastrointestinal outbreak among hospital staff in Homer, Alaska. The objectives of this study were to identify the outbreak source and prevent future illness.
View Article and Find Full Text PDFWe compared the mortality risk in Alaska among persons with symptomatic coronavirus disease 2019 (COVID-19) during the period the Delta variant was predominant to the risk among those with symptomatic COVID-19 before Delta predominance. The Delta period was associated with 2.43-fold higher odds of death.
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